Chemoinformatics in Drug Discovery

Chemoinformatics in Drug Discovery

4.11 - 1251 ratings - Source

This handbook provides the first-ever inside view of today's integrated approach to rational drug design. Chemoinformatics experts from large pharmaceutical companies, as well as from chemoinformatics service providers and from academia demonstrate what can be achieved today by harnessing the power of computational methods for the drug discovery process. With the user rather than the developer of chemoinformatics software in mind, this book describes the successful application of computational tools to real-life problems and presents solution strategies to commonly encountered problems. It shows how almost every step of the drug discovery pipeline can be optimized and accelerated by using chemoinformatics tools -- from the management of compound databases to targeted combinatorial synthesis, virtual screening and efficient hit-to-lead transition. An invaluable resource for drug developers and medicinal chemists in academia and industry.References 1 BROWN, F. Chemoinformatics: What is it and How does it impact drug discovery. ... 1999, 3, 379a€“383. ... 6 OPREA, T.I. Chemical space navigation in lead discovery. ... 9 PEARLMAN, R.S. CONCORD Usera#39;s Manual. ... RILEY, D.P. Rational design of synthetic enzymes and their potential utility as human pharmaceuticals: development of manganese(II)-based superoxide dismutase mimics.

Title:Chemoinformatics in Drug Discovery
Author: Tudor I. Oprea
Publisher:John Wiley & Sons - 2006-03-06

You must register with us as either a Registered User before you can Download this Book. You'll be greeted by a simple sign-up page.

Once you have finished the sign-up process, you will be redirected to your download Book page.

How it works:
  • 1. Register a free 1 month Trial Account.
  • 2. Download as many books as you like (Personal use)
  • 3. Cancel the membership at any time if not satisfied.

Click button below to register and download Ebook
Privacy Policy | Contact | DMCA